By Pavel A. Pevzner (auth.), Raffaele Giancarlo, Sridhar Hannenhalli (eds.)
This e-book constitutes the refereed complaints of the seventh overseas Workshop on Algorithms in Bioinformatics, WABI 2007, held in Philadelphia, PA, united states in September 2007.
The 38 revised complete papers provided including the summary of a keynote speak have been rigorously reviewed and chosen from 133 submissions. All present problems with algorithms in bioinformatics are addressed, starting from mathematical instruments to experimental reviews of approximation algorithms and stories on major computational analyses. a number of organic difficulties are handled, together with genetic mapping, series alignment and series research, phylogeny, comparative genomics, and protein constitution. in addition the papers function high-performance computing techniques to computationally challenging studying and optimization difficulties in bioinformatics and canopy tools, software program and dataset repositories for improvement and trying out of such algorithms and their underlying models.
Read Online or Download Algorithms in Bioinformatics: 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007. Proceedings PDF
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Additional resources for Algorithms in Bioinformatics: 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007. Proceedings
Topits: threading one-dimensional predictions into three-dimensional structures. Proc. Int. Conf. Intell. Syst. Mol. Biol. : The abundance of short proteins in the mammalian proteome. : Glimmers in the midnight zone: characterization of aligned identical residues in sequence-dissimilar proteins sharing a common fold. Proc. Int. Conf. Intell. Syst. Mol. Biol. : The universal protein resource (uniprot): an expanding universe of protein information. Nucleic Acids Res. : Motif Extraction and Protein Classiﬁcation.
Identiﬁcation of common molecular subsequences. J. Mol. Biol. : The prosite database. Nucleic Acids Res. : Expasy: The proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res. : Protein secondary structure prediction based on position-speciﬁc scoring matrices. J. Mol. Biol. : Hiding behind hydrophobicity. transmembrane segments in mass spectrometry. J. Biol. Chem. : Conserved sequence motifs of olfactory receptor-like proteins may participate in upstream and downstream signal transduction.
The general problem to compute a set of 3D coordinates consistent with some given contact map has been shown to be NP-hard . A series of heuristic algorithms have been developed to solve the problem. Galaktinov and Marshall  reconstructed the structures of ﬁve small proteins by adopting information relative to the residue coordination numbers. Other approaches rely on steepest descent with inequality distance constraints  and on an algorithm that minimizes a continuous cost function that embodies constraints associated with contact and angle maps , respectively.
Algorithms in Bioinformatics: 7th International Workshop, WABI 2007, Philadelphia, PA, USA, September 8-9, 2007. Proceedings by Pavel A. Pevzner (auth.), Raffaele Giancarlo, Sridhar Hannenhalli (eds.)